---
title: "Martin Weigt"
type: "entity"
entity_kind: "person"
status: "hub"
writer_model: "claude-sonnet-5"
canonical_name: "Martin Weigt"
aliases: []
first_seen: "2026-07-23T00:00:00.000Z"
connects_to: ["direct coupling analysis","phylogenetic bias","protein coevolution","epistasis","Edwin Rodriguez Horta"]
---


Computational biophysicist (Sorbonne Université, per the originating capture's attribution — not independently re-verified this session) working on statistical-inference methods for protein coevolution, including Direct Coupling Analysis. He matters to this vault as co-author, with Edwin Rodriguez Horta, of the first primary check the vault holds on whether phylogenetic sampling bias explains DCA's known weakness at long-range contact prediction — a direct methodological complement to the vault's existing Bravi/Wyart DCA-epistasis cluster, though the two research lines are otherwise independent.

## References

- [[claim-dca-strongest-couplings-only-weakly-influenced-by-phylogenetic-bias]] — the 2021 phylogenetic-bias finding.
- [[observation-dca-and-ib-gaps-are-estimand-vs-estimator-stories-resolved-oppositely]] — the bridge note this finding feeds.