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Edward Egelman

Structural biologist (University of Virginia), a specialist in cryo-EM reconstruction of helical protein filaments, and co-author with Nikhil Malvankar on both papers that overturned the Geobacter conductive-pili model: the OmcS cytochrome-filament structure (Cell, 2019) and the secretory-pili structure (Nature, 2021). Matters to this vault as the methodological engine behind the reversal — the Geobacter nanowire question flipped when cryo-EM could image the filament directly rather than infer its composition, and Egelman is the recurring cryo-EM name on both resolved structures.

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